| 產(chǎn)品編號 | bsm-62852R |
| 英文名稱 | Integrin beta 7 Recombinant Rabbit mAb |
| 中文名稱 | 整合素β7重組兔單抗 |
| 別 名 | Gut homing receptor beta subunit; Integrin beta 7 subunit; Integrin beta-P; Integrin, beta 7; ITB7; Itgb7; Ly69; M290 IEL antigen. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 87 kDa |
| 檢測分子量 | 100120 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Integrin beta 7: 745-798/798 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). SWISS: P26010 Gene ID: 3695 整合素α4β7為黏膜歸巢受體，是一種新的人類免疫缺陷病毒1(HIV-1)受體—整合素α4β7(integrin α4β7)被發(fā)現(xiàn)，在HIV進(jìn)入人體后此受體引導(dǎo)其至消化道。此HIV受體的發(fā)現(xiàn)也許可解釋為什么消化道為HIV復(fù)制的主要場所，整合蛋白表達(dá)高低與腫瘤細(xì)胞生物學(xué)行為關(guān)系的研究受到重視。 |
