| 產(chǎn)品編號(hào) | bsm-62889R |
| 英文名稱 | Phospho-LRP6 (Ser1490) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化低密度脂蛋白受體相關(guān)蛋白6重組兔單抗 |
| 別 名 | Low-density lipoprotein receptor-related protein 7. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 180 kDa |
| 檢測(cè)分子量 | 210180 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human LRP6 around the phosphorylation site of S1490: PPP-pS-PAT |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. SWISS: O75581 Gene ID: 4040 |
| 產(chǎn)品圖片 |
Western blot analysis of heLa treated with Calyculin cell lysate. Using Phospho-LRP6 (Ser1490) (bsm-62889R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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