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Jun D Rabbit pAb (bs-1393R)  
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產品編號 bs-1393R
英文名稱 Jun D Rabbit pAb
中文名稱 活化蛋白激酶D抗體
別    名 Transcription factor jun-D; jun D proto-oncogene; JUND1; AP-1; JUND; JUND1; MGC6245; MGC72300; AP 1; AP1; jun D proto oncogene; JunD FL isoform; JUND_HUMAN; Transcription factor jun D; transcription factor jun-D isoform JunD-FL; Jun-like transcription factor; pfam03957.  
研究領域 腫瘤  免疫學  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Rat (predicted: Human,Mouse,Rabbit,Cow,Chicken,Dog)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Jun D: 245-347/347 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. [provided by RefSeq, Jul 2008]

Function:
Transcription factor binding AP-1 sites.

Subunit:
Binds DNA as a dimer. Interacts with MEN1; this interaction represses transcriptional activation.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the bZIP family. Jun subfamily.
Contains 1 bZIP (basic-leucine zipper) domain.

SWISS:
P17535

Gene ID:
3727

Database links:

Entrez Gene: 3727 Human

Entrez Gene: 16478 Mouse

Entrez Gene: 24518 Rat

Omim: 165162 Human

SwissProt: P17535 Human

SwissProt: P15066 Mouse

SwissProt: P52909 Rat

Unigene: 2780 Human

Unigene: 419851 Mouse

Unigene: 46225 Rat



轉錄調節(jié)因子(Transcriptin Regulators)
Jun-D屬于轉錄因子AP-1家族(Jun蛋白家族包括c-Jun、JunB和JunD)
產品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat adrenal gland); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Jun D) Polyclonal Antibody, Unconjugated (bs-1393R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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