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Blood Group Antigen Precursor Rabbit pAb (bs-7589R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號 bs-7589R
英文名稱 Blood Group Antigen Precursor Rabbit pAb
中文名稱 血型抗原前體蛋白抗體
別    名 A transferase; Abo; ABO blood group(transferase A alpha 1-3 N acetylgalactosaminyltransferase transferase B alpha 1 3 galactosyltransferase); ABO glycosyltransferase; B(A) alpha 1, 3 glactosyltransferase; B transferase; BGAT_HUMAN; Fucosylglycoprotein 3 a  
Specific References  (1)     |     bs-7589R has been referenced in 1 publications.
[IF=0] Almgren et al. Genetic determinants of circulating GIP and GLP-1 concentrations. (2017) JCI.Insight. 2  IHC ;  Human.  
研究領(lǐng)域 心血管  細(xì)胞生物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Chimpanzee)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Blood Group Antigen Precursor: 51-150/354 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Function:
This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

Subcellular Location:
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.

Post-translational modifications:
The soluble form derives from the membrane form by proteolytic processing.

Similarity:
Belongs to the glycosyltransferase 6 family.

SWISS:
P16442

Gene ID:
28

Database links:

Entrez Gene: 28 Human

Entrez Gene: 80908 Mouse

Entrez Gene: 65270 Rat

Omim: 110300 Human

SwissProt: P16442 Human

SwissProt: P38649 Mouse

SwissProt: Q9ET32 Rat

Unigene: 654423 Human

Unigene: 160386 Mouse

Unigene: 112591 Rat



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