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PCDHA7 Rabbit pAb (bs-11121R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-11121R
英文名稱 PCDHA7 Rabbit pAb
中文名稱 原鈣粘附蛋白α7抗體
別    名 CNRS4; PCDA7_HUMAN; PCDH alpha 7; PCDH-alpha-7; PCDHA7; Protocadherin alpha 7; Protocadherin alpha-7.  
研究領域 神經生物學  信號轉導  細胞粘附分子  細胞骨架  細胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat)
產品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 98 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PCDHA7: 601-700/937 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin (PCDH) gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protein products of PCDH-alpha genes interact with Integrin ∫1 to promote cell adhesion and form oligomers with PCDH-gamma proteins at specific membrane sites. PCDHA7 (Protocadherin alpha-7) is a 937 amino acid single-pass transmembrane protein that contains six cadherin domains and functions as a potential calcium-dependent cell-adhesion protein, possibly playing a role in the creation and maintenance of neuronal connections. There are two isoforms of PCDHA7 that are produced as a result of alternative splicing events.

Function:
Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subunit:
Contains 6 cadherin domains.

Subcellular Location:
Cell membrane.

Similarity:
Contains 6 cadherin domains.

SWISS:
Q9UN72

Gene ID:
56141

Database links:

Entrez Gene: 56141 Human

Omim: 606313 Human

SwissProt: Q9UN72 Human

Unigene: 199343 Human



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