| 產(chǎn)品編號(hào) | bs-12140R |
| 英文名稱 | DLGAP4 Rabbit pAb |
| 中文名稱 | PSD95結(jié)合蛋白4抗體 |
| 別 名 | DLGAP4; DAP 4; DAP-4; DAP4; Discs, large(Drosophila) homolog associated protein 4; Disks large associated protein 4; Disks large-associated protein 4; DLGAP4; DLGP4_HUMAN; DLP4; PSD 95/SAP90 binding protein 4; PSD-95/SAP90-binding protein 4; RP5-977B1.6; |
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Specific References (1) | bs-12140R has been referenced in 1 publications.
[IF=4.996] Dong, Cairong. et al. DLGAP4 acts as an effective prognostic predictor for hepatocellular carcinoma and is closely related to tumour progression. SCI REP-UK. 2022 Nov;12(1):1-14 IHC ; Human.
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| 研究領(lǐng)域 | 神經(jīng)生物學(xué) 通道蛋白 細(xì)胞膜受體 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Pig,Sheep,Cow,Dog,GuineaPig,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 108 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SAPAP4/DLGAP4: 261-370/992 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP4 is a 992 amino acid protein that likely localizes to the postsynaptic membrane of neurons to enhance neuronal signaling. SAPAP4 could act as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP4, DLGAP4, maps to human chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception. Function: May play a role in the molecular organization of synapses and neuronal cell signaling. Could be an adapter protein linking ion channel to the subsynaptic cytoskeleton. May induce enrichment of PSD-95/SAP90 at the plasma membrane. Subunit: Interacts with DLG1 and DLG4/PSD-95 (By similarity). Subcellular Location: Membrane; Peripheral membrane protein (By similarity). Similarity: Belongs to the SAPAP family. SWISS: Q9Y2H0 Gene ID: 22839 Database links: Entrez Gene: 22839 Human Entrez Gene: 228836 Mouse SwissProt: Q9Y2H0 Human SwissProt: B1AZP2 Mouse Unigene: 249600 Human Unigene: 22094 Mouse Unigene: 11279 Rat |
| 產(chǎn)品圖片 |
Sample:
Muscle (Mouse) Lysate at 40 ug
Primary: Anti- DLGAP4(bs-12140R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 108 kD
Observed band size: 108 kD
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