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Argonaute 3 Rabbit pAb (bs-12517R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-12517R
英文名稱 Argonaute 3 Rabbit pAb
中文名稱 真核翻譯起始因子2C3抗體
別    名 eIF2C3; Argonaute 3/eIF2C 3; 5730550L01Rik; Ago 3; Ago3; AGO3_HUMAN; argonaute 3; Argonaute3; eIF 2C 3; eIF-2C 3; eIF2C 3; Eif2c3; eIF2C3; EIF2C3 protein; Eukaryotic translation initiation factor 2C 3; Eukaryotic translation initiation factor 2C3; FLJ12765; hAgo3; MGC86946; Protein argonaute-3.  
Specific References  (1)     |     bs-12517R has been referenced in 1 publications.
[IF=3.1] Gong et al. Identification and verification of potential piRNAs from domesticated yak testis. (2018) Reproduction. 155:117-127  WB, IHC-P ;  Yak.  
研究領域 細胞生物  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Chicken,Dog,Horse,Danio rerio)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 97 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Argonaute 3/eIF2C3: 251-350/860 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

Subunit:
Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the argonaute family. Ago subfamily.
Contains 1 PAZ domain.
Contains 1 Piwi domain.

SWISS:
Q9H9G7

Gene ID:
192669

Database links:

Entrez Gene: 192669 Human

Entrez Gene: 214150 Mouse

Entrez Gene: 313593 Rat

Omim: 607355 Human

SwissProt: Q9H9G7 Human

SwissProt: Q8CJF9 Mouse

Unigene: 657659 Human

Unigene: 440915 Mouse

Unigene: 482388 Mouse

Unigene: 483093 Mouse

Unigene: 92025 Rat



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