| 產(chǎn)品編號 | bs-13605R |
| 英文名稱 | ZNF206 Rabbit pAb |
| 中文名稱 | 鋅指蛋白206抗體 |
| 別 名 | Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc Finger Protein 206; ZSCAN10; ZSC10_HUMAN. |
| 研究領(lǐng)域 | 細胞生物 神經(jīng)生物學(xué) 干細胞 轉(zhuǎn)錄調(diào)節(jié)因子 鋅指蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 80 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZNF206: 551-650/725 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF206 (zinc finger protein 206), also known as ZSCAN10 (zinc finger and SCAN domain containing 10), is a 725 amino acid protein that contains one SCAN box domain and 14 C2H2-type zinc fingers. Localized to the nucleus, ZNF206 is thought to play a role in transcriptional regulation events. The gene encoding ZNF206 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. Function: Znf206 is a zinc finger protein and probable transcriptional regulator. It is expressed in embryonic stem cells and downregulated upon differentiation. Both Oct4 and Sox2 bind the znf206 gene. Subunit: Interacts with POU5F1/OCT4 and SOX2 (By similarity). Subcellular Location: Nuclear Similarity: Contains 14 C2H2-type zinc fingers. Contains 1 SCAN box domain. SWISS: Q96SZ4 Gene ID: 84891 Database links: Entrez Gene: 84891 Human Entrez Gene: 332221 Mouse SwissProt: Q96SZ4 Human SwissProt: Q20D61 Mouse Unigene: 334515 Human Unigene: 270315 Mouse |
