產(chǎn)品編號(hào) | bs-14662R |
英文名稱 | EXOC6 Rabbit pAb |
中文名稱 | EXOC6蛋白抗體 |
別 名 | DKFZp761I2124; EXOC 6; EXOC6A; Exocyst complex component 6; Exocyst complex component Sec15A; FLJ1125; FLJ11251; MGC33397; SEC15; SEC15 like 1; SEC15 like protein 1; SEC15 like protein 3; SEC15A; EXOC6_HUMAN; SEC15L; SEC15L1; SEC15L3; Sec15p. |
研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 94 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human EXOC6: 711-804/804 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] Function: EXOC6 is a component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane. Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8. Interacts with CNTRL. Interacts with RAB11A in a GTP-dependent manner (By similarity). Similarity: Belongs to the SEC15 family. SWISS: Q8TAG9 Gene ID: 54536 Database links: Entrez Gene: 54536 Human Entrez Gene: 107371 Mouse Omim: 609672 Human SwissProt: Q8TAG9 Human SwissProt: Q8R313 Mouse |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EXOC6) Polyclonal Antibody, Unconjugated (bs-14662R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (EXOC6) Polyclonal Antibody, Unconjugated (bs-14662R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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