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MEST Rabbit pAb (bs-18797R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-18797R
英文名稱 MEST Rabbit pAb
中文名稱 中胚層特異性轉(zhuǎn)錄同源蛋白MEST抗體
別    名 DKFZp686L18234; EC 3.-.-.-; Mesoderm specific transcript(mouse) homolog; Mesoderm specific transcript homolog(mouse); Mesoderm-specific transcript homolog protein; MEST; MEST_HUMAN; MGC111102; MGC8703; OTTHUMP00000210362; OTTHUMP00000210364; OTTHUMP000002  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  淋巴細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 39 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MEST: 101-200/335 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15. [provided by RefSeq, Dec 2011]

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in hydatidiform moles, but barely expressed in dermoid cysts. Biallelic expression is detected in blood lymphocytes. Seems to imprinted in an isoform-specific manner rather than in a tissue-specific manner in lymphocytes. Isoform 1 is expressed only from the paternal allele. Isoform 2 is expressed from both the paternal allele and the maternal allele.

Similarity:
Belongs to the AB hydrolase superfamily.

SWISS:
Q5EB52

Gene ID:
4232

Database links:

Entrez Gene: 4232 Human

Entrez Gene: 404180 Cow

Entrez Gene: 607717 Dog

Entrez Gene: 17294 Mouse

Entrez Gene: 100147710 Pig

Entrez Gene: 58827 Rat

Omim: 601029 Human

SwissProt: Q2HJM9 Cow

SwissProt: Q5EB52 Human

SwissProt: Q07646 Mouse

SwissProt: Q6P5P5 Rat

Unigene: 270978 Human

Unigene: 59431 Rat



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