| 產(chǎn)品編號(hào) | bs-19546R |
| 英文名稱 | NUP53 Rabbit pAb |
| 中文名稱 | 核孔復(fù)合蛋白Nup53抗體 |
| 別 名 | 35 kDa nucleoporin; Mitotic phosphoprotein 44; MP 44; MP-44; NP 44; NP44; Nuclear pore complex protein 53kDa; Nuclear pore complex protein Nup 53; Nuclear pore complex protein Nup53; Nuclear pore protein NUP 53; Nuclear pore protein NUP53; Nucleoporin 35k |
| 研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 38 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NUP53: 241-326/326 |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the nucleoporin family. The encoded protein contains two membrane binding regions, is localized to the nuclear rim, and is part of the nuclear pore complex. All molecules entering or leaving the nucleus either diffuse through or are actively transported by the nuclear pore complex. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 7 and 10. [provided by RefSeq, Dec 2013] Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs). Can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC. Subcellular Location: Nucleus > nuclear pore complex. Nucleus membrane. Tightly associated with the nuclear membrane and lamina. Similarity: Belongs to the Nup53 family. Contains 1 RRM Nup35-type domain. SWISS: Q8NFH5 Gene ID: 129401 Database links: Entrez Gene: 129401 Human Entrez Gene: 100054143 Horse Entrez Gene: 69482 Mouse Entrez Gene: 337461 Zebrafish Omim: 608140 Human SwissProt: Q8NFH5 Human SwissProt: Q8R4R6 Mouse SwissProt: Q6P6X9 Zebrafish Unigene: 180591 Human Unigene: 29200 Mouse Unigene: 203627 Rat Unigene: 5851 Zebrafish |
