| 產(chǎn)品編號(hào) | bs-21015R |
| 英文名稱 | Pannexin 1 Rabbit pAb |
| 中文名稱 | 間隙連接蛋白PANX1抗體 |
| 別 名 | innexin; MRS1; Pannexin 1; Pannexin-1; Panx1; PANX1_HUMAN; PX1; UNQ2529. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 細(xì)胞粘附分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 48 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Pannexin 1: 61-106/426 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties. [provided by RefSeq, Jul 2008] Function: Structural component of the gap junctions and the hemichannels. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Subunit: Homohexamer. Forms homomeric or PANX1/PANX2-heteromeric intercellular channels on coexpression in paired Xenopus oocytes (By similarity). Subcellular Location: Cell membrane. Cell junction > gap junction. Endoplasmic reticulum membrane. Similarity: Belongs to the pannexin family. SWISS: Q96RD7 Gene ID: 24145 Database links: Entrez Gene: 24145 Human Entrez Gene: 55991 Mouse Entrez Gene: 100171730 Orangutan Omim: 608420 Human SwissProt: Q96RD7 Human SwissProt: Q9JIP4 Mouse SwissProt: Q5REE3 Orangutan Unigene: 591976 Human Unigene: 142253 Mouse Unigene: 204521 Rat |
| 產(chǎn)品圖片 |
Sample:Muscle (Mouse)Lysate at 40 ug
Primary: Anti-Pannexin 1(bs-21015R)at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 48kD
Observed band size: 53kD
|
