產(chǎn)品編號 | bs-9962R |
英文名稱 | PDE4C Rabbit pAb |
中文名稱 | 磷酸二酯酶4C抗體 |
別 名 | DPDE 1; DPDE1; MGC126222; PDE 21; PDE 4C; PDE21; Pde4c; PDE4C_HUMAN; phosphodiesterase 4C; phosphodiesterase 4C cAMP specific; phosphodiesterase 4C, cAMP specific(phosphodiesterase E1 dunce homolog, Drosophila); phosphodiesterase E1 dunce homolog; phosphodiesterase E1 dunce homolog Drosophila; phosphodiesterase type 4C. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 80 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PDE4C: 1-100/712 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] Function: Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Tissue Specificity: Expressed in various tissues but not in cells of the immune system. Similarity: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily. SWISS: Q08493 Gene ID: 5143 Database links: Entrez Gene: 5143 Human Entrez Gene: 110385 Mouse Omim: 600128 Human SwissProt: Q08493 Human SwissProt: Q3UEI1 Mouse Unigene: 132584 Human Unigene: 255180 Mouse Unigene: 214181 Rat Unigene: 92465 Rat |