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PDE4C Rabbit pAb (bs-9962R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-9962R
英文名稱 PDE4C Rabbit pAb
中文名稱 磷酸二酯酶4C抗體
別    名 DPDE 1; DPDE1; MGC126222; PDE 21; PDE 4C; PDE21; Pde4c; PDE4C_HUMAN; phosphodiesterase 4C; phosphodiesterase 4C cAMP specific; phosphodiesterase 4C, cAMP specific(phosphodiesterase E1 dunce homolog, Drosophila); phosphodiesterase E1 dunce homolog; phosphodiesterase E1 dunce homolog Drosophila; phosphodiesterase type 4C.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 80 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE4C: 1-100/712 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Function:
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.

Tissue Specificity:
Expressed in various tissues but not in cells of the immune system.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.

SWISS:
Q08493

Gene ID:
5143

Database links:

Entrez Gene: 5143 Human

Entrez Gene: 110385 Mouse

Entrez Gene: 290646 Rat

Omim: 600128 Human

SwissProt: Q08493 Human

SwissProt: Q3UEI1 Mouse

SwissProt: P14644 Rat

Unigene: 132584 Human

Unigene: 255180 Mouse

Unigene: 214181 Rat

Unigene: 92465 Rat



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