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PTPLB Rabbit pAb (bs-4429R)  
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產(chǎn)品編號(hào) bs-4429R
英文名稱 PTPLB Rabbit pAb
中文名稱 蛋白酪氨酸磷酸酶PTPLB抗體
別    名 3 hydroxyacyl CoA dehydratase 2; 3-hydroxyacyl-CoA dehydratase 2; HACD2; HACD2_HUMAN; Protein tyrosine phosphatase like(proline instead of catalytic arginine) member b; Protein tyrosine phosphatase like member B; Protein-tyrosine phosphatase-like member B; PTPLB; Very-long-chain(3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PTPLB: 181-254/254 <Cytoplasmic>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene can catalyze the third step (dehydration) in the conversion of long chain fatty acids to very long chain fatty acids. The encoded protein localizes to the endoplasmic reticulum membrane. [provided by RefSeq, Jul 2016]

Function:
Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung.

Similarity:
Belongs to the very long-chain fatty acids dehydratase HACD family.

SWISS:
Q6Y1H2

Gene ID:
201562

Database links:

Entrez Gene: 201562 Human

Entrez Gene: 70757 Mouse

SwissProt: Q6Y1H2 Human

SwissProt: Q9D3B1 Mouse

Unigene: 705480 Human

Unigene: 27286 Mouse



產(chǎn)品圖片
Sample: Du145(Human) Cell Lysate at 30 ug Primary: Anti-PTPLB (bs-4429R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD
Sample: LOVO(Human) Cell Lysate at 30 ug Primary: Anti-PTPLB (bs-4429R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PTPLB) Polyclonal Antibody, Unconjugated (bs-4429R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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