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RABGGTA Rabbit pAb (bs-21088R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-21088R
英文名稱 RABGGTA Rabbit pAb
中文名稱 RABGGTA蛋白抗體
別    名 Geranylgeranyl transferase type 2 subunit alpha; Geranylgeranyl transferase type II subunit alpha; Geranylgeranyl transferase type-2 subunit alpha; PGTA_HUMAN; Protein prenyltransferase alpha subunit repeat containing 3; PTAR3; Rab geranyl geranyltransferase subunit alpha; Rab geranyl-geranyltransferase subunit alpha; Rab geranylgeranyltransferase alpha subunit; Rab geranylgeranyltransferase subunit alpha; Rab GG transferase alpha; Rab GGTase alpha; RABGGTA.  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human,Mouse (predicted: Rat,Pig)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 65 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RABGGTA: 131-330/567 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 RABGGTA (Rab Geranylgeranyltransferase Subunit Alpha) is a Protein Coding gene. Diseases associated with RABGGTA include Choroideremia. Among its related pathways are Gene Expression and Signaling events mediated by PRL. Gene Ontology (GO) annotations related to this gene include Rab GTPase binding and protein prenyltransferase activity.

Function:
Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Similarity:
Belongs to the protein prenyltransferase subunit alpha family.
Contains 5 LRR (leucine-rich) repeats.
Contains 6 PFTA repeats.

SWISS:
Q92696

Gene ID:
5875

Database links:

Entrez Gene: 516619 Cow

Entrez Gene: 5875 Human

Entrez Gene: 56187 Mouse

Entrez Gene: 100174130 Orangutan

Entrez Gene: 100049679 Pig

Entrez Gene: 58983 Rat

Omim: 601905 Human

SwissProt: Q5EA80 Cow

SwissProt: Q92696 Human

SwissProt: Q9JHK4 Mouse

SwissProt: Q5NVK5 Orangutan

SwissProt: A5A779 Pig

SwissProt: Q08602 Rat

Unigene: 7696 Cow

Unigene: 377992 Human

Unigene: 87216 Mouse

Unigene: 536 Orangutan

Unigene: 45681 Pig

Unigene: 29434 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (RABGGTA) Polyclonal Antibody, Unconjugated (bs-21088R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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