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FPR1 Rabbit pAb (bs-23519R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產(chǎn)品編號 bs-23519R
英文名稱 FPR1 Rabbit pAb
中文名稱 甲酸基肽受體1抗體
別    名 Formyl peptide receptor 1; fMet Leu Phe receptor; FMLP; FMLP Receptor; FPR 1; FPR; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; fMet-Leu-Phe receptor; FMLPR; FPR; FPR receptor; FPR1; FPR1_MOUSE; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor.  
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 40 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from mouse FPR1: 131-230/364 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010]

Function:
High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Similarity:
Cell membrane; Multi-pass membrane protein.

Database links:
UniProtKB - P33766 

轉(zhuǎn)錄調(diào)節(jié)因子(Transcriptin Regulators) FPR1屬于G蛋白偶聯(lián)受體家族成員,參與細胞信號傳導(dǎo),激活MAPK通路,免疫應(yīng)答。
產(chǎn)品圖片
Sample: Spleen (Mouse) Lysate at 40 ug Primary: Anti-FPR1 (bs-23519R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 55 kD
Sample: BV-2(Mouse) Cell Lysate at 30 ug Primary: Anti-FPR1 (bs-23519R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kD Observed band size: 55 kD
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