產(chǎn)品編號 | IHC0132H |
英文名稱 | Human CEACAM5 Ready-To-Use IHC Kit |
中文名稱 | 人癌胚抗原即用型免疫組化試劑盒 |
性 狀 | Liquid |
種 屬 | Human |
應(yīng)用范圍 | Immunohistochemistry |
適用樣品基質(zhì) | FFPE tissue |
描述 | IHC0132H is a ready-to-use IHC kit for staining of human CEACAM5. The kit provides all reagents, from antigen retrieval to cover slip mounting, that require little to no diluting or handling prior to use. Simply apply the reagents to your sample slide according to the protocol and you're steps away from obtaining high-quality IHC data. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. SWISS: P06731 Gene ID: 1048 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0132H (Human CEACAM5 IHC Kit).
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