| 產(chǎn)品編號 |
V0102-HRP |
| 英文名稱 |
CRP Mouse mAb, HRP conjugated
|
| 中文名稱 |
HRP標記的C-反應蛋白單克隆抗體 |
| 別 名 |
C-reactive protein; C Reactive Protein; C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1. C反應蛋白 |
| 克 隆 號 |
5D12 |
| 理論分子量 |
kDa |
| 檢測分子量 |
|
| 性 狀 |
Liquid |
| 濃 度 |
1mg/ml |
| 緩 沖 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated in innate immunity. CRP binds to ligands containing phosphocholine, SAP binds to amyloid fibrils, DNA, chromatin, fibronectin, C4-binding proteins and glycosaminoglycans. "Long" pentraxins have N-terminal extensions to the common pentraxin domain; one group, the neuronal pentraxins, may be involved in synapse formation and remodeling, and they may also be able to form heteromultimers.
C反應蛋白 CRP（C-reactive protin）是與C性肺炎球菌的多糖起反應的一種蛋白，在某些細菌的感染過程中出現(xiàn)在血漿中。
CRP是在一些病理性情況下出現(xiàn)于病人血清中的一種糖蛋白，特別是在伴有肯炎癥和組織壞死疾病的急性期。血清中出現(xiàn)的這種異常蛋白能和肺炎C-多糖體發(fā)生沉淀反應，當疾病好轉(zhuǎn)或緩解時，CRP減低或消失。
臨床意義:
(1)各種急性化膿性炎癥、菌血癥、組織壞死(心肌梗塞、手術、嚴重創(chuàng)傷、燒傷等)、惡性腫瘤、結締組織病、腎移殖后急性排異反應、急性風濕熱、風濕性關節(jié)炎、類風濕性關節(jié)炎、心
|
|
|
