| 產(chǎn)品編號(hào) | D53900 |
| 英文名稱 | Fludarabine Phosphate |
| 中文名稱 | 磷酸氟達(dá)拉濱 |
| 別 名 | F-ara-A (NSC 312887) Phosphate; fludara Phosphate; F-ara-AMP; NSC 312887 Phosphate |
| 克 隆 號(hào) | |
| CAS | 75607-67-9 |
| 理論分子量 | 365.21 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Fludarabine Phosphate is the phosphate salt of a fluorinated nucleotide antimetabolite analog of the antiviral agent vidarabine (ara-A) with antineoplastic activity. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase alpha, ribonucleotide reductase, and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth. |
