| 產(chǎn)品編號(hào) | D53925 |
| 英文名稱(chēng) | Tyrphostin 8 |
| 中文名稱(chēng) | 4-羥基苯亞甲基丙二腈 |
| 別 名 | 4-Hydroxybenzylidenemalononitrile |
| 克 隆 號(hào) | |
| CAS | 3785-90-8 |
| 理論分子量 | 170.17 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances transferrin receptor-mediated transcytosis in Caco-2 cells, and increases the hypoglycemic effect of oral insulin-transferrin. hypoglycemic effect. |
