產(chǎn)品編號(hào) | IHC0690H |
英文名稱(chēng) | Human Cyclin B1 Ready-To-Use IHC Kit |
中文名稱(chēng) | 人周期素B1即用型免疫組化試劑盒 |
別 名 | Ccn-2; CCNB; CCNB1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb-4; Cycb-5; CycB1; Cycb1-rs1; I79_013589; CCNB1_HUMAN; G2 mitotic specific cyclin B1; G2/mitotic-specific cyclin-B |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs). Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis. It is essential for the control of the cell cycle at the G2/M transition. Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis. Destruction of Cyclin B1 is required for cell cycle progression. Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer. SWISS: P14635 Gene ID: 891 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human brain tissue slide using IHC0690H (Human Cyclin B1 Kit).
Immunohistochemical analysis of paraffin embedded Human colon cancer tissue slide using IHC0690H (Human Cyclin B1 Kit).
Immunohistochemical analysis of paraffin embedded Human tonsil tissue slide using IHC0690H (Human Cyclin B1 Kit).
Immunohistochemical analysis of paraffin embedded Human thymus tissue slide using IHC0690H (Human Cyclin B1 Kit).
Immunohistochemical analysis of paraffin embedded Human esophagus tissue slide using IHC0690H (Human Cyclin B1 Kit).
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