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Rabbit Anti-KLF13/FITC Conjugated antibody (bs-1577R-FITC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1577R-FITC
英文名稱 Rabbit Anti-KLF13/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的腸道內(nèi)富含的Kruppel樣因子13
別    名 Basic transcription element binding protein 3; BTE binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; NSLP1; RANTES factor of late activated T lymphocytes 1; RFLAT-1; RFLAT 1; RFLAT1; Transcription factor NSLP1; KLF13_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KLF13
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Kruppel-like factor 13 (KLF13) belongs to a family of transcription factors that contain three classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by two cysteines and two histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes. KLF13 appears to be an important component of the transcription network required for heart development and cholesterol homeostasis.

Function:
Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells.

Subcellular Location:
Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Phosphorylated.

Similarity:
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Contains 3 C2H2-type zinc fingers.

Database links:

Entrez Gene: 51621 Human

Entrez Gene: 50794 Mouse

Omim: 605328 Human

SwissProt: Q9Y2Y9 Human

SwissProt: Q9JJZ6 Mouse

Unigene: 525752 Human

Unigene: 240473 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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