| 產(chǎn)品編號(hào) | bs-1065R-BF647 |
| 英文名稱 | Rabbit Anti-C9orf127/BF647 Conjugated antibody |
| 中文名稱 | BF647標(biāo)記的鼻咽癌細(xì)胞相關(guān)基因6抗體 |
| 別 名 | NGX6; 4930500O05Rik; C9orf127; MGC120460; NAG-5; NGX6; RGD1310012; RP11-112J3.10; TMEM8B; nasopharyngeal carcinoma; NPC associated gene 6; TMM8B_HUMAN; chromosome 9 open reading frame 127; NAG 5; Nasopharyngeal carcinoma expressed 6; Nasopharyngeal carcinoma related protein; Nasopharyngeal carcinoma-associated gene 6 protein; Protein NAG-5; Protein NGX6; RP11-112J3.10; RP11-112J3.10-001; TMEM8B; Transmembrane protein 8B . |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Cow, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 52kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NGX6 N-terminus |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: NGX6 (nasopharyngeal carcinoma/NPC associated gene 6) may function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. [SUBUNIT] Isoform 2 (via its cytoplasmic part) interacts with EZR. [SUBCELLULAR LOCATION] Isoform 2: Cell membrane; Multi-pass membrane protein (Probable). Cytoplasm (Probable). Nucleus (Probable). Mitochondrion. Endoplasmic reticulum. Belongs to the NGX6 family. The down-regulation of C9orf127 may be closely associated with tumorigenesis and metastasis of colorectal carcinoma. However, it may not contribute to the development and progression of gastric carcinoma. Function: May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. Subunit: Isoform 2 (via its cytoplasmic part) interacts with EZR. Subcellular Location: Cell membrane. Cytoplasm. Nucleus. Mitochondrion. Endoplasmic reticulum. Also detected in mitochondrion and endoplasmic reticulum. Post-translational modifications: Isoform 2 is N-glycosylated. Similarity: Belongs to the TMEM8 family. Contains 1 EGF-like domain. Database links: Entrez Gene: 51754 Human Entrez Gene: 242409 Mouse SwissProt: A6NDV4 Human SwissProt: B1AWJ5 Mouse Unigene: 493808 Human Unigene: 171489 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. NGX6是鼻咽癌發(fā)生和發(fā)展重要的相關(guān)蛋白,NGX-6作用于鼻咽癌細(xì)胞，抗體可用于鼻咽癌診斷。有學(xué)者認(rèn)為：NGX6也表達(dá)在部分消化系統(tǒng)的腫瘤中。 |
