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Rabbit Anti-NSBP1/Gold Conjugated antibody (bs-0700R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-0700R-Gold
英文名稱 Rabbit Anti-NSBP1/Gold Conjugated antibody
中文名稱 膠體金標記的核小體結合蛋白1抗體
別    名 Nucleosome-binding protein 1; Nucleosome-binding protein 45; NBP-45; GARP45 protein; HMGN5_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 免疫學  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NSBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
NSBP1 binds specifically to nuclear core particles and acts as a transcriptional activator. [Subcellular Location] Nucleus. [Tissue Specificity] Widely expressed with highest levels in submaxillary gland, thymus, kidney and liver and lowest levels in brain, lung, pancreas and eye. [Developmental Stage] Highest levels are found in 7-day-old embryos. Levels in the 7-day-old embryo are 4-fold higher than in the adult and almost 10-fold higher than in later embryonic stages. [SIMILARITY] Belongs to the HMGN family.

Function:
Preferentially binds to euchromatin and modulates cellular transcription by counteracting linker histone-mediated chromatin compaction (By similarity).

Subcellular Location:
Nucleus. Note=Associates with nucleosomes in euchromatin and is largely excluded from constitutive heterochromatin (By similarity).

Tissue Specificity:
Ubiquitously expressed.

Similarity:
Belongs to the HMGN family.

Database links:

Entrez Gene: 79366 Human

Omim: 300385 Human

SwissProt: P82970 Human

Unigene: 282204 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

NSBP-1主要用于前列腺疾病方面的研究。
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