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Rabbit Anti-GPIHBP1/BF555 Conjugated antibody (bs-16276R-BF555)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-16276R-BF555
英文名稱 Rabbit Anti-GPIHBP1/BF555 Conjugated antibody
中文名稱 BF555標記的高密度脂蛋白結合蛋白1抗體
別    名 Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GPI anchored HDL binding protein 1; GPI anchored High Density Lipid binding protein 1; GPI HBP1; GPI-anchored HDL-binding protein 1; GPI-HBP1; GPIHBP1; Hbp1; HDBP1_HUMAN; High density lipoprotein-binding protein 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  細胞生物  免疫學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 18kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPIHBP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1) is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons. Consisting of 184 amino acids, GPIHBP1 is a single-pass membrane protein that may be regulated by dietary factors and by PPARγ. Mutations in the gene encoding GPIHBP1 are linked to chylomicronemia syndrome, a rare genetic disorder caused by LPL deficiency and is characterized by enlarged liver and spleen, inflammation of the pancreas, fatty deposits under the skin and possibly deposits in the retina of the eye.

Function:
Plays a key role in the lipolytic processing of chylomicrons.

Subunit:
Binds with high affinity to high-density lipoprotein (HDL) (By similarity). Binds to lipoprotein lipase (LPL), chylomicrons and APOA5.

Subcellular Location:
Cell membrane. Localized at the cell surface.

Post-translational modifications:
Glycosylation of Asn-78 is critical for cell surface localization and the binding of chylomicrons and lipoprotein lipase (By similarity).

Similarity:
Contains 1 UPAR/Ly6 domain.

Database links:

Entrez Gene: 338328 Human

SwissProt: Q8IV16 Human

Unigene: 426410 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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